RESEARCH SHOWS E-CIGARETTE VAPE INCREASES HARMFUL LUNG BACTERIA
19 December 2019
Researchers from Queen’s have discovered that bacteria often found in the lungs became more harmful and caused increased inflammation when they were exposed to e-cigarette vape.
The results of the three-year study, published (18.12.19) in Respiratory Research, show that this increase in lung inflammation is due to bacteria made more virulent by exposure to e-cigarette vapour.
Dr Deirdre Gilpin, researcher and lecturer from the School of Pharmacy at Queen’s and lead author of the research explained: “There is currently a knowledge gap about whether vaping is harmful, or less harmful than smoking tobacco.
“Bacteria have long been associated with the development of lung diseases such as bronchitis and pneumonia where smoking plays a role.
“Our study is the first of its kind which aimed to compare the effect of cigarette smoke and e-cigarette vapour on key lung bacteria.”
Vaping has been suggested as a safer alternative to smoking but there is limited evidence to support this and there are major concerns around its safety.
As rates of tobacco smoking have decreased the number of people vaping has increased. Vapers are not always ex-smokers, and there has been an increase of vaping among young people who have never smoked before.
According to the World Health Organization, there has been a small but steady decrease in the estimated number of smokers globally, to just over one billion. Whereas the number of vapers has been increasing rapidly – from about seven million in 2011 to 41 million in 2018.
The study compared the effect of exposure to cigarette smoke extract and e-cigarette vapour on levels of inflammation and the virulence of bacteria commonly associated with lung disease.
The research team found that exposure to both cigarette smoke extract and e-cigarette vapour caused an increase in the potential of bacteria to cause harm in the lungs, in a way which could lead to diseases such as COPD (Chronic Obstructive Pulmonary Disease) and asthma.
The researchers also found that changes in bacteria exposed to e-cigarette vapour were similar, and in some cases exceeded those observed following bacterial exposure to cigarette smoke, suggesting that there is little difference between cigarette smoke and e-cigarette vapour.
Dr Gilpin added: “This study shows us that vaping may carry the same risk as cigarette smoke in increasing the susceptibility to bacterial infection.”
Professor Jose Bengoechea, Director of the Wellcome-Wolfson Institute for Experimental Medicine at Queen’s and co-author of the study said: “This is a study with phenomenal public health implications.
“Worryingly, e-cigarette vapour as well as cigarette smoke increase the harmful potential of already dangerous infections, in addition to the well-known detrimental effect on lung function.
“At the very least this work should open a frank debate on vaping safety.”
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